Rabbit Monoclonal Antibody to Junctional Adhesion Molecule 1

包装: 1G|100G|500G|1KG|100KG

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别名:F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Description

Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Specification
Aliases	F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321
Entrez GeneID	50848
Swissprot	Q9Y624
WB Predicted band size	Calculated MW: 33 kDa; Observed MW: 33 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human Junctional Adhesion Molecule 1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of Junctional Adhesion Molecule 1/JAMA in K562, PC-3 lysates using Junctional Adhesion Molecule 1 antibody.
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Junctional Adhesion Molecule 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.