库存-现货
瑞威尔生物科技 REVERE

Rabbit Monoclonal Antibody to KDM4B

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别名:KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B
应用:WB,IHC,ICC
反应种属:Human
规格:50μl/100μl

Description
Histone demethylase that specifically demethylates ‘Lys-9’ of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 ‘Lys-4’, H3 ‘Lys-27’, H3 ‘Lys-36’ nor H4 ‘Lys-20’. Only able to demethylate trimethylated H3 ‘Lys-9’, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Specification
Aliases KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B
Entrez GeneID 23030
Swissprot O94953
WB Predicted band size Calculated MW: 122 kDa; Observed MW: 150 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthetic peptide of human KDM4B/JMJD2B
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Application
WB 1/500-1/1000
IHC 1/50-1/100
ICC 1/50-1/200

Western blot analysis of KDM4B in 293, COS7 lysates using KDM4B antibody.
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using KDM4B/JMJD2B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。