Rabbit Monoclonal Antibody to Lamin B Receptor

包装: 1G|100G|500G|1KG|100KG

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400-880-2824

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别名:PHA; LMN2R; TDRD18; DHCR14B; LBR
应用:WB,IHC,IP
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Description

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Specification
Aliases	PHA; LMN2R; TDRD18; DHCR14B; LBR
Entrez GeneID	3930
Swissprot	Q14739
WB Predicted band size	Calculated MW: 71 kDa; Observed MW: 71 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human Lamin B Receptor
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of Lamin B Receptor in K562, Hela lysates using Lamin B Receptor antibody.
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Lamin B Receptor antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.