Rabbit Monoclonal Antibody to LAMP1

包装: 1G|100G|500G|1KG|100KG

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别名:LAMP1; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
LAMP1 and LAMP2 (lysosome-associated membrane protein 1 and 2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplam and contains a tyrosine sorting motif which targets LAMP to lysosomal membranes.

Description

LAMP1 and LAMP2 (lysosome-associated membrane protein 1 and 2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplam and contains a tyrosine sorting motif which targets LAMP to lysosomal membranes.

Specification
Aliases	LAMP1; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a
Entrez GeneID	3916
Swissprot	P11279
WB Predicted band size	Calculated MW: 45 kDa; Observed MW: 90-120 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human LAMP1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of LAMP1 in Hela lysates using LAMP1 antibody.
	Immunohistochemistry analysis of paraffin-embedded Human tonsil using LAMP1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.