Rabbit Monoclonal Antibody to M-CSF Receptor

包装: 1G|100G|500G|1KG|100KG

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别名:M-CSF Receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.

Description

Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.

Specification
Aliases	M-CSF Receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115
Entrez GeneID	12978
Swissprot	P09581
WB Predicted band size	Calculated MW: 109 kDa; Observed MW: 109 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Recombinant protein of mouse MCSF Receptor
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA