中文 
别名:Methylated-DNA–protein-cysteine methyltransferase应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O(6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents. |
| Specification | |
|---|---|
| Aliases | Methylated-DNA–protein-cysteine methyltransferase |
| Entrez GeneID | 4255 |
| Swissprot | P16455 |
| WB Predicted band size | Calculated MW: 22 kDa; Observed MW: 22 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human MGMT |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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Western blot analysis of MGMT in Jurkat lysates using MGMT antibody. |
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Immunohistochemistry analysis of paraffin-embedded Human colon cancer using MGMT antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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