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瑞威尔生物科技 REVERE

Rabbit Monoclonal Antibody to MLKL

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别名:MLKL
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Specification
Aliases MLKL
Entrez GeneID 197259
Swissprot Q8NB16
WB Predicted band size Calculated MW: 54 kDa; Observed MW: 54 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Recombinant protein of human MLKL
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Application
WB 1/500-1/1000

Western blot analysis of MLKL in HT-29 lysates using MLKL antibody.
Western blot analysis of MLKL in U251MG, Hela lysates using MLKL antibody.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。