Rabbit Monoclonal Antibody to NEK9

包装: 1G|100G|500G|1KG|100KG

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400-880-2824

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别名:NC; APUG; NERCC; LCCS10; NERCC1
应用:WB,IHC,ICC
反应种属:Human,Rat
规格：50μl/100μl

Description
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.

Description

Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.

Specification
Aliases	NC; APUG; NERCC; LCCS10; NERCC1
Entrez GeneID	91754
Swissprot	Q8TD19
WB Predicted band size	Calculated MW: 107 kDa; Observed MW: 107 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	A synthetic peptide of human NEK9
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of NEK9 in rat skeletal muscle lysates using NEK9 antibody.
	Western blot analysis of NEK9 in Hela lysates using NEK9 antibody
	Immunocytochemistry analysis of NEK9 (green) in HT-1080 using NEK9 antibody,and DAPI(blue).
	Immunohistochemistry analysis of paraffin-embedded Human colon cancer using NEK9 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.