Rabbit Monoclonal Antibody to Paxillin

包装: 1G|100G|500G|1KG|100KG

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别名:PXN; Paxillin
应用:WB,IHC,ICC,IP
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.

Description

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.

Specification
Aliases	PXN; Paxillin
Entrez GeneID	5829
Swissprot	P49023
WB Predicted band size	Calculated MW: 65 kDa; Observed MW: 65 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic peptide of human Paxillin
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Paxillin in mouse lung lysates using Paxillin antibody.
	Western blot analysis of Paxillin in C6 lysates using Paxillin antibody.
	Immunocytochemistry analysis of Paxillin (green) in hela using Paxillin antibody,and DAPI(blue).
	Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Paxillin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.