Rabbit Monoclonal Antibody to Phospho-AKT (Ser473)

包装: 1G|100G|500G|1KG|100KG

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别名:AKT; PKB; RAC; PRKBA; PKB-ALPHA; RAC-ALPHA
应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Description

Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Specification
Aliases	AKT; PKB; RAC; PRKBA; PKB-ALPHA; RAC-ALPHA
Entrez GeneID	207
clone	4H6
WB Predicted band size	56kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Ser473 of human AKT1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA