Rabbit Monoclonal Antibody to Phospho-CREB (Ser133)

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:CREB; CREB-1
应用:WB,IHC
反应种属:Human,Rat
规格：50μl/100μl

Description
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Specification
Aliases	CREB; CREB-1
Entrez GeneID	1385
clone	3C4
WB Predicted band size	Calculated MW: 35 kDa; Observed MW: 43 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Ser133 of human CREB
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/1000
IHC	1/50

	Western blot analysis of Phospho-CREB (Ser133) in C6, C6+UV lysates using Phospho-CREB (Ser133) antibody.
	Western blot analysis of Phospho-CREB (Ser133) in CHO-K1 lysates using Phospho-CREB (Ser133) antibody.
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using CREB (Phospho-Ser133) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.