Rabbit Monoclonal Antibody to Phospho-delta 1 Catenin (Thr916)

包装: 1G|100G|500G|1KG|100KG

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别名:CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
应用:WB,IHC,ICC
反应种属:Human,Mouse
规格：50μl/100μl

Description
Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.

Description

Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.

Specification
Aliases	CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
Entrez GeneID	1500
Swissprot	O60716
WB Predicted band size	Calculated MW: 108 kDa; Observed MW: 100 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Thr916 of human delta 1 Catenin/CAS
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Phospho-delta 1 Catenin/CAS (Thr916) in MCF-7, U251, C2C12 lysates using Phospho-delta 1 Catenin (Thr916) antibody.
	Immunocytochemistry analysis of delta 1 Catenin/CAS (Phospho-Thr916) (green) in hela using delta 1 Catenin/CAS (Phospho-Thr916) antibody,and DAPI(blue)
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-delta 1 Catenin/CAS (Thr916) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.