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瑞威尔生物科技 REVERE

Rabbit Monoclonal Antibody to Phospho-Histone H2A.X (Ser139)

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别名:H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X
应用:WB,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Specification
Aliases H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X
Entrez GeneID 3014
Swissprot P16104
WB Predicted band size Calculated MW: 15 kDa; Observed MW: 15 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human gamma H2A.X
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Application
IP 1/20
WB 1/500-1/1000

Western blot analysis of gamma H2A.X (Phospho-Ser139) in HepG2 lysates using Phospho-Histone H2A.X (Ser139) antibody.
Western blot analysis of gamma H2A.X (Phospho-Ser139) in Jurkat, THP-1, C6, 3T3 lysates using gamma H2A.X (Phospho-Ser139) antibody.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。