别名:H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X应用:WB,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl
| Description |
|---|
| Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. |
| Specification | |
|---|---|
| Aliases | H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X |
| Entrez GeneID | 3014 |
| Swissprot | P16104 |
| WB Predicted band size | Calculated MW: 15 kDa; Observed MW: 15 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human gamma H2A.X |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
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Western blot analysis of gamma H2A.X (Phospho-Ser139) in HepG2 lysates using Phospho-Histone H2A.X (Ser139) antibody. |
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Western blot analysis of gamma H2A.X (Phospho-Ser139) in Jurkat, THP-1, C6, 3T3 lysates using gamma H2A.X (Phospho-Ser139) antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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