Rabbit Monoclonal Antibody to PKC beta 2

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta
应用:WB,IHC,ICC,IP
反应种属:Human,Rat
规格：50μl/100μl

Description
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at ‘Ser-559’, ‘Ser-644’ and ‘Ser-652’.

Description

Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at ‘Ser-559’, ‘Ser-644’ and ‘Ser-652’.

Specification
Aliases	PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta
Entrez GeneID	5579
Swissprot	P05771
WB Predicted band size	Calculated MW: 77 kDa; Observed MW: 77 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	A synthesized peptide derived from human PKC beta 2
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of PKC beta 2 in rat brain lysates using PKC beta 2 antibody.Observed band size:77kDa.
	Western blot analysis of PKC beta 2 in Hela, A549, U2OS, U87-MG lysates using PKC beta 2 antibody
	Immunocytochemistry analysis of PKC beta 2 (green) in K562 using PKC beta 2 antibody,and DAPI(blue).
	Immunohistochemistry analysis of paraffin-embedded Human tonsil using PKC beta 2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.