Rabbit Monoclonal Antibody to PKR

包装: 1G|100G|500G|1KG|100KG

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别名:EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
应用:WB,IHC,ICC,IP
反应种属:Human
规格：50μl/100μl

Description
PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.

Specification
Aliases	EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Entrez GeneID	5610
Swissprot	P19525
WB Predicted band size	Calculated MW: 62 kDa; Observed MW: 74 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human PKR
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of PKR in K562, Hela lysates using PKR antibody.
	Immunocytochemistry analysis of PKR(green) in Hela using PKR antibody,and DAPI(blue)
	Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using PKR antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.