Rabbit Monoclonal Antibody to Ubiquitin K63

包装: 1G|100G|500G|1KG|100KG

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别名:FLJ25987; MGC8385; ubiquitin B; Ubiquitin; UBCEP1; UBCEP2; RPS27A
应用:WB,IHC,ICC
反应种属:Human
规格：50μl/100μl

Description
Plays an important role in the ubiquitin-proteasome pathway. Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1; the activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, then from E2 to ubiquitin ligase E3 for final delivery to the epsilon-NH2 of the target protein lysine residue.

Description

Plays an important role in the ubiquitin-proteasome pathway. Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1; the activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, then from E2 to ubiquitin ligase E3 for final delivery to the epsilon-NH2 of the target protein lysine residue.

Specification
Aliases	FLJ25987; MGC8385; ubiquitin B; Ubiquitin; UBCEP1; UBCEP2; RPS27A
Entrez GeneID	7314
Swissprot	P0CG47
WB Predicted band size	Calculated MW: 26 kDa; Observed MW: 8 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human Ubiquitin (linkage-specific K63)
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of Ubiquitin (linkagespecific K63) in Hela, A549 lysates using Ubiquitin K63 antibody.
	Immunocytochemistry analysis of Ubiquitin (linkagespecific K63) (green) in hela using Ubiquitin (linkagespecific K63) antibody,and DAPI(blue)
	Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Ubiquitin (linkagespecific K63) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.