Rabbit Monoclonal Antibody to WTAP

包装: 1G|100G|500G|1KG|100KG

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别名:hFL(2)D; WT1-associated protein; Wilms tumor 1-associating protein; Pre-mRNA-splicing regulator WTAP
应用:WB,IHC,IP
反应种属:Human
规格：50μl/100μl

Description
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms.

Description

The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms.

Specification
Aliases	hFL(2)D; WT1-associated protein; Wilms tumor 1-associating protein; Pre-mRNA-splicing regulator WTAP
Entrez GeneID	9589
Swissprot	Q15007
WB Predicted band size	Calculated MW: 44 kDa; Observed MW: 55 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Recombinant protein of human WTAP
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of WTAP in K562, Hela lysates using WTAP antibody.
	Immunohistochemistry analysis of paraffin-embedded Human tonsil using WTAP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.