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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to 53BP1 (Ab-29)

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别名:p53-binding protein 1; P531; TP53B; TP53BP1; TRP53BP1
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.Iwabuchi K., J. Biol. Chem. 273:26061-26068(1998).Nakajima D., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Bechtel S., BMC Genomics 8:399-399(2007).
Specification
Aliases p53-binding protein 1; P531; TP53B; TP53BP1; TRP53BP1
Entrez GeneID 7158;
Swissprot Q12888
WB Predicted band size 170kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide derived from Internal of human 53BP1.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000

Western blot analysis of extracts from Jurkat cells and HUVEC cells, using 53BP1 (Ab-29) antibody P41741.
Western blot analysis of extracts from 293 cells (Lane 2), using 53BP1 (Ab-29) antiobdy P41741. The lane on the left is treated with synthesized peptide.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。