库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to ABCB4

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别名:GBD1; ICP3; MDR2; MDR3; PGY3; ABC21; MDR2/3; PFIC-3
应用:IHC
反应种属:Human
规格:50μl/100μl

Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Specification
Aliases GBD1; ICP3; MDR2; MDR3; PGY3; ABC21; MDR2/3; PFIC-3
Swissprot P21439
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic peptide of human ABCB4
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/50-1/300
ELISA 1/5000-1/10000

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P12593(ABCB4 Antibody) at dilution 1/70. (Original magnification: ×200)

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。