Rabbit Polyclonal Antibody to ABCB8

包装: 1G|100G|500G|1KG|100KG

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别名:ATP-binding cassette sub-family B member 8, MABC1, M-ABC1, EST328128
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

Specification
Aliases	ATP-binding cassette sub-family B member 8, MABC1, M-ABC1, EST328128
Entrez GeneID	11194;
Swissprot	Q9NUT2
WB Predicted band size	76kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein corresponding to a region derived from 394-693 amino acids of Human ATP-binding cassette sub-family B member 8
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/500-1/2000
IHC	1/25-1/100
ELISA	1:2000-1:5000

	Gel: 8%SDS-PAGELane1: Hela cell lysate Lane2: HepG2 cell lysateLysates: 20 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Donkey anti Rabbit IgG – H&L (HRP) at 1/3000 dilutionExposure time: 1 minute
	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 31025(ABCB8 Antibody) at dilution 1/17, on the right is treated with the fusion protein.