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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to ACCN3 (N-term)

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别名:Acid-sensing ion channel 3, ASIC3, hASIC3, Amiloride-sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Testis sodium channel 1, hTNaC1, ASIC3, ACCN3, SLNAC1, TNAC1
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a member of the degenerin/epithelial
sodium channel (DEG/ENaC) superfamily. The members of this family
are amiloride-sensitive sodium channels that contain intracellular
N and C termini, two hydrophobic transmembrane regions, and a large
extracellular loop, which has many cysteine residues with conserved
spacing. The member encoded by this gene is an acid sensor and may
play an important role in the detection of lasting pH changes. In
addition, a heteromeric association between this member and ACCN1
has been observed as proton-gated channels sensitive to gadolinium.
Alternative splicing of this gene generates three transcript
variants encoding distinct isoforms.
Specification
Aliases Acid-sensing ion channel 3, ASIC3, hASIC3, Amiloride-sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Testis sodium channel 1, hTNaC1, ASIC3, ACCN3, SLNAC1, TNAC1
Entrez GeneID 9311
Swissprot Q9UHC3
WB Predicted band size 58.9kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This ACCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ACCN3.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

ACCN3 Antibody (N-term) (Cat. #P32161) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ACCN3 antibody detected the ACCN3 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。