库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to ACE2

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别名:ACEH
应用:IHC
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible.
Specification
Aliases ACEH
Swissprot Q9BYF1
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human ACE2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/50-1/200
ELISA 1/5000-1/10000

The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P03714(ACE2 Antibody) at dilution 1/80. (Original magnification: ×200)

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。