别名:Antigen NY-CO-13; Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53应用:WB,ICC,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl
| Description |
|---|
| Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. |
| Specification | |
|---|---|
| Aliases | Antigen NY-CO-13; Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53 |
| Entrez GeneID | 7157 |
| Swissprot | P04637 |
| WB Predicted band size | Calculated MW: 44 kDa; Observed MW: 53 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human p53 (acetyl K370) |
| Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
| ICC | 1/50-1/200 |
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Western blot analysis of p53 (acetyl K370) in HeLa lysates treated with Trichostatin A using Acetyl-p53 (Lys370) antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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