别名:ACN; ACINUS; fSAP152应用:WB,IHC
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Specification | |
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Aliases | ACN; ACINUS; fSAP152 |
Entrez GeneID | 22985; |
Swissprot | Q9UKV3 |
WB Predicted band size | 152kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human apoptotic chromatin condensation inducer 1 |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
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Gel: 8%SDS-PAGE Lysate: 40ug 231 cell Primary antibody: 1/550 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute |
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Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using P42839 at dilution 1/30. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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