Rabbit Polyclonal Antibody to ACOT8

包装: 1G|100G|500G|1KG|100KG

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别名:hTE; PTE1; PTE2; PTE-1; PTE-2; HNAACTE; hACTE-III
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes.

Description

The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes.

Specification
Aliases	hTE; PTE1; PTE2; PTE-1; PTE-2; HNAACTE; hACTE-III
Swissprot	O14734
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human ACOT8
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/15-1/50
ELISA	1/1000-1/2000

	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P00841(ACOT8 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00841(ACOT8 Antibody) at dilution 1/20. (Original magnification: ×200)