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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to ACTL7A (N-term)

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别名:Actin-like protein 7A, Actin-like-7-alpha, ACTL7A
应用:WB
反应种属:Human
规格:50μl/100μl

Description
ACTL7A is a member of a family
of actin-related proteins (ARPs) which share significant amino acid
sequence identity to conventional actins. Both actins and ARPs have
an actin fold, which is an ATP-binding cleft, as a common feature.
The ARPs are involved in diverse cellular processes, including
vesicular transport, spindle orientation, nuclear migration and
chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B,
are intronless, and are located approximately 4 kb apart in a
head-to-head orientation within the familial dysautonomia candidate
region on 9q31. Based on mutational analysis of the ACTL7A gene in
patients with this disorder, it was concluded that it is unlikely
to be involved in the pathogenesis of dysautonomia. The ACTL7A gene
is expressed in a wide variety of adult tissues, however, its exact
function is not known.
Specification
Aliases Actin-like protein 7A, Actin-like-7-alpha, ACTL7A
Entrez GeneID 10881
Swissprot Q9Y615
WB Predicted band size 48.6kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

ACTL7A Antibody (N-term) (Cat. #P30790) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ACTL7A antibody detected the ACTL7A protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。