别名:Actin-like protein 7A, Actin-like-7-alpha, ACTL7A应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known. |
| Specification | |
|---|---|
| Aliases | Actin-like protein 7A, Actin-like-7-alpha, ACTL7A |
| Entrez GeneID | 10881 |
| Swissprot | Q9Y615 |
| WB Predicted band size | 48.6kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
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ACTL7A Antibody (N-term) (Cat. #P30790) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ACTL7A antibody detected the ACTL7A protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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