Rabbit Polyclonal Antibody to AK7

包装: 1G|100G|500G|1KG|100KG

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别名:Adenylate kinase 7, AK 7, ATP-AMP transphosphorylase 7, AK7
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The adenylate kinases (AK) are a family of structurally and functionally related enzymes that catalyze a similar reaction, MgNTP + AMP = MgNDP + ADP (N = A or G). The AK enzymes are important for maintenance of homeostasis of the adenine and guanine nucleotide pools. AK1 is a cytosolic enzyme for which ATP is the substrate. AK2 catalyzes the same reaction as AK1, but it is localized in the mitochondrial intermembrane space. AK3 is present in the mitochondrial matrix and prefers GTP over ATP as the substrate.

Description

The adenylate kinases (AK) are a family of structurally and functionally related enzymes that catalyze a similar reaction, MgNTP + AMP = MgNDP + ADP (N = A or G). The AK enzymes are important for maintenance of homeostasis of the adenine and guanine nucleotide pools. AK1 is a cytosolic enzyme for which ATP is the substrate. AK2 catalyzes the same reaction as AK1, but it is localized in the mitochondrial intermembrane space. AK3 is present in the mitochondrial matrix and prefers GTP over ATP as the substrate.

Specification
Aliases	Adenylate kinase 7, AK 7, ATP-AMP transphosphorylase 7, AK7
Entrez GeneID	122481
Swissprot	Q96M32
WB Predicted band size	82.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This AK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-656 amino acids from the C-terminal region of human AK7.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application
WB	1/1000
IHC	1/100-1/500

	Western blot analysis of anti-AK7 Antibody (C-term) (Cat.#P30313) in K562 cell line lysates (35ug/lane).AK7(arrow) was detected using the purified Pab.
	AK7 Antibody (C-term) (Cat. #P30313) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AK7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.