中文 
别名:SSeCKS; AKAP250应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| Specification | |
|---|---|
| Aliases | SSeCKS; AKAP250 |
| Entrez GeneID | 9590; |
| Swissprot | Q02952 |
| WB Predicted band size | 191kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to residues near the C terminal of human A kinase (PRKA) anchor protein 12 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/50-1/200 |
 |
Gel: 8%SDS-PAGE Lysate: 40ug HT-29 cell Primary antibody: 1/600 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds |
 |
Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42903 at dilution 1/40. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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