Rabbit Polyclonal Antibody to AKAP7

包装: 1G|100G|500G|1KG|100KG

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别名:AKAP18;18-kD;AKA7G
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[

Description

This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[

Specification
Aliases	AKAP18;18-kD;AKA7G
Entrez GeneID	9465;
Swissprot	Q9P0M2
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein corresponding to residues near the N terminal of human A kinase (PRKA) anchor protein 7
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
IHC	115-1/50

	Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42798 at dilution 1/15.
	Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42798 at dilution 1/15.