中文 
别名:AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB’s regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. |
| Specification | |
|---|---|
| Aliases | AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS |
| Entrez GeneID | 64400 |
| Swissprot | Q9H8T0 |
| WB Predicted band size | 33.1kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
 |
Western blot analysis of lysates from human heart tissue lysate, U-251 MG cell line (from left to right), using AKTIP Antibody (C-term)(Cat. #P32216). P32216 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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