Rabbit Polyclonal Antibody to alpha 1 Fetoprotein

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .

Description

Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .

Specification
Aliases	Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
Entrez GeneID	174
Swissprot	P02771
WB Predicted band size	Calculated MW: 69 kDa; Observed MW: 69 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	The antiserum was produced against synthesized peptide derived from the Internal region of human AFP. AA range:371-420
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ELISA	1/10000

	Western blot analysis of alpha 1 Fetoprotein in mouse liver, mouse serum lysates using alpha 1 Fetoprotein antibody.
	Immunohistochemistry analysis of paraffin-embedded rat brain using alpha 1 Fetoprotein antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
	Immunohistochemistry analysis of paraffin-embedded mouse brain using alpha 1 Fetoprotein antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
	Immunohistochemistry analysis of paraffin-embedded mouse brain using alpha 1 Fetoprotein antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.