Rabbit Polyclonal Antibody to Androgen Receptor (Ab-363)

包装: 1G|100G|500G|1KG|100KG

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别名:ANDR; Androgen receptor; DHTR; Dihydrotestosterone receptor; NR3C4
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.Lubahn D.B., Mol. Endocrinol. 2:1265-1275(1988).Lubahn D.B., Proc. Natl. Acad. Sci. U.S.A. 86:9534-9538(1989).Govindan M.V.; Mol. Endocrinol. 4:417-427(1990).

Description

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.Lubahn D.B., Mol. Endocrinol. 2:1265-1275(1988).Lubahn D.B., Proc. Natl. Acad. Sci. U.S.A. 86:9534-9538(1989).Govindan M.V.; Mol. Endocrinol. 4:417-427(1990).

Specification
Aliases	ANDR; Androgen receptor; DHTR; Dihydrotestosterone receptor; NR3C4
Entrez GeneID	367;
Swissprot	P10275
WB Predicted band size	85kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized non-phosphopeptide derived from human Androgen Receptor around the phosphorylation site of tyrosine 363 (D-Y-Y(p)-N-F).
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.