Rabbit Polyclonal Antibody to Angiopoietin 1

包装: 1G|100G|500G|1KG|100KG

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别名:ANGPT1; KIAA0003; Angiopoietin-1; ANG-1
应用:WB
反应种属:Human,Rat
规格：50μl/100μl

Description
Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.

Description

Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.

Specification
Aliases	ANGPT1; KIAA0003; Angiopoietin-1; ANG-1
Entrez GeneID	284
Swissprot	Q15389
WB Predicted band size	Calculated MW: 58 kDa; Observed MW: 58 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	A synthesized peptide derived from human Angiopoietin 1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.