Rabbit Polyclonal Antibody to ANKK1

包装: 1G|100G|500G|1KG|100KG

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别名:Ankyrin repeat and protein kinase domain-containing protein 1; EC 2.7.11.1; Protein kinase PKK2; X-kinase; Sugen kinase 288
应用:WB
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.Neville M.J., Hum. Mutat. 23:540-545(2004).Dubertret C., Schizophr. Res. 67:75-85(2004).Manning G., Science 298:1912-1934(2002).

Description

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.Neville M.J., Hum. Mutat. 23:540-545(2004).Dubertret C., Schizophr. Res. 67:75-85(2004).Manning G., Science 298:1912-1934(2002).

Specification
Aliases	Ankyrin repeat and protein kinase domain-containing protein 1; EC 2.7.11.1; Protein kinase PKK2; X-kinase; Sugen kinase 288
Entrez GeneID	255239;
Swissprot	Q8NFD2
WB Predicted band size	84kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human ANKK1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.