中文 
别名:APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| APC, WNT signaling pathway regulator(APC) Homo sapiens This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008], |
| Specification | |
|---|---|
| Aliases | APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5 |
| Entrez GeneID | 324 |
| Swissprot | P25054 |
| WB Predicted band size | 311kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | The antiserum was produced against synthesized peptide derived from human APC around the phosphorylation site of Ser2054. AA range:2020-2069 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Application | |
|---|---|
| WB | 1/500 – 1/2000 |
| IHC | 1/100 – 1/300 |
| ELISA | 1/40000 |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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