Rabbit Polyclonal Antibody to APLNR

包装: 1G|100G|500G|1KG|100KG

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别名:APJ; APJR; HG11; AGTRL1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Description

This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Specification
Aliases	APJ; APJR; HG11; AGTRL1
Entrez GeneID	187;
Swissprot	P35414
WB Predicted band size	43kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein corresponding to a region derived from internal residues of human apelin receptor
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/200-1/1000
IHC	115-1/50

	Gel: 10%SDS-PAGE Lysate: 40ug OP9 cell Primary antibody: 1/250 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 minutes
	Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42758 at dilution 1/20.