Rabbit Polyclonal Antibody to ARBK1

包装: 1G|100G|500G|1KG|100KG

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别名:ADRBK1; ARBK1; BARK; BARK1; Beta-ARK-1
应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).Penn R.B., J. Biol. Chem. 269:14924-14930(1994).Fushman D., J. Biol. Chem. 273:2835-2843(1998).

Description

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).Penn R.B., J. Biol. Chem. 269:14924-14930(1994).Fushman D., J. Biol. Chem. 273:2835-2843(1998).

Specification
Aliases	ADRBK1; ARBK1; BARK; BARK1; Beta-ARK-1
Entrez GeneID	156;
Swissprot	P25098
WB Predicted band size	80kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from internal of human ARBK1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.