别名:ARHGB; glutamate transporter EAAT4-associated protein 48; GTRAP48; PDZ-RhoGEF; rho guanine exchange factor (GEF) 11应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.Nagase T., DNA Res. 4:141-150(1997).Gregory S.G., Nature 441:315-321(2006).Ruemenapp U., FEBS Lett. 459:313-318(1999). |
Specification | |
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Aliases | ARHGB; glutamate transporter EAAT4-associated protein 48; GTRAP48; PDZ-RhoGEF; rho guanine exchange factor (GEF) 11 |
Entrez GeneID | 9826; |
Swissprot | O15085 |
WB Predicted band size | 170kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from N-terminal of human ARHGEF11. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from A549 cells and COLO 205 cells, using ARHGEF11 antibody P42569. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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