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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to ARHGEF12

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别名:ARHGC; ARHGEF12; Leukemia-associated RhoGEF; RHO guanine nucleotide exchange factor (GEF) 12 (LARG); Rho guanine nucleotide exchange factor 12
应用:WB
反应种属:Human,Mouse
规格:50μl/100μl

Description
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.Kourlas P.J., Proc. Natl. Acad. Sci. U.S.A. 97:2145-2150(2000).The MGC Project Team, Genome Res. 14:2121-2127(2004).Nagase T., DNA Res. 4:141-150(1997).
Specification
Aliases ARHGC; ARHGEF12; Leukemia-associated RhoGEF; RHO guanine nucleotide exchange factor (GEF) 12 (LARG); Rho guanine nucleotide exchange factor 12
Entrez GeneID 23365;
Swissprot Q9NZN5
WB Predicted band size 173kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human ARHGEF12.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000

Western blot analysis of extracts from RAW264.7 cells, using ARHGEF12 antibody P42570.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。