库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to ARIH1

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别名:ARI; HARI; HHARI; UBCH7BP
应用:IHC
反应种属:Human, Mouse
规格:50μl/100μl

Description
ARIH1 (ariadne homolog), also known as ubiquitin conjugating enzyme E2 binding protein 1, ARI, HARI, HHARI (human homolog of Drosophila ariadne), MOP-6 (monocyte protein 6) or UBCH7BP (UBCH7 binding protein), is a 557 amino acid cytoplasmic protein. Expressed in a wide variety of tissues, ARIH1 contains two RING-type zinc fingers and one IBR (in-between RING fingers)-type domain. ARIH1 is believed to be involved in protein degradation and protein translation. ARIH1 interacts with UBCH7 and is thought to function as an E3 ubiquitin-protein ligase (or as a component of an E3 complex) that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme (UBCH7) and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, ARIH1 interacts with and polyubiquitylates eIF4E2, thereby targeting it for proteasomal degradation.
Specification
Aliases ARI; HARI; HHARI; UBCH7BP
Swissprot Q9Y4X5
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human ARIH1
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/50-1/100
ELISA 1/5000-1/10000

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06245(ARIH1 Antibody) at dilution 1/30. (Original magnification: ×200)

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。