库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to Arrestin-β-1 (phospho Ser412)

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别名:ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1
应用:WB,IHC
反应种属:Human,Monkey
规格:50μl/100μl

Description
arrestin beta 1(ARRB1) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],
Specification
Aliases ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1
Entrez GeneID 408
Swissprot P49407
WB Predicted band size 47kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Monkey
Immunogen The antiserum was produced against synthesized peptide derived from human Arrestin 1 around the phosphorylation site of Ser412. AA range:369-418
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application
WB 1/500 – 1/2000
IHC 1/100 – 1/300
ELISA 1/10000


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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。