Rabbit Polyclonal Antibody to ASAP3 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1, ASAP3, DDEFL1, UPLC1
应用:WB,IHC
反应种属:Human, Hamster
规格：50μl/100μl

Description
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.

Description

This gene encodes a member of a subfamily of
ADP-ribosylation factor(Arf) GTPase-activating proteins that
contain additional ankyrin repeat and pleckstrin homology domains.
The Arf GAP domain of this protein catalyzes the hydrolysis of GTP
bound to Arf proteins. The encoded protein promotes cell
differentiation and migration and has been implicated in cancer
cell invasion. Alternative splicing results in multiple transcript
variants.

Specification
Aliases	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1, ASAP3, DDEFL1, UPLC1
Entrez GeneID	55616
Swissprot	Q8TDY4
WB Predicted band size	99.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Hamster
Immunogen	This ASAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human ASAP3.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	ASAP3 Antibody (N-term) (Cat. #P30890) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow).
	ASAP3 Antibody (N-term) (Cat. #P30890) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow).
	ASAP3 antibody (N-term) (Cat. #P30890) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ASAP3 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.