别名:ATX1, D6S504E, SCA1应用:WB
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function. |
Specification | |
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Aliases | ATX1, D6S504E, SCA1 |
Entrez GeneID | 6310; |
Swissprot | P54253 |
WB Predicted band size | 87kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Peptide sequence around phosphorylation site of Serine 776 (R-W-S(p)-A-P) derived from Human Ataxin 1. |
Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/1000 |
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Western blot analysis of extracts from HepG2 cells using Ataxin 1 (Phospho-Ser776) Antibody P40658.The lane on the left is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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