Rabbit Polyclonal Antibody to ATBP3

包装: 1G|100G|500G|1KG|100KG

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别名:Cancer-associated gene protein; ATP-binding domain-containing protein 3; ATPBD3;
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.Yousef G.M., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).

Description

Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.Yousef G.M., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).

Specification
Aliases	Cancer-associated gene protein; ATP-binding domain-containing protein 3; ATPBD3;
Entrez GeneID	90353;
Swissprot	Q7Z7A3
WB Predicted band size	36kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from C-terminal of human ATBP3.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.