中文 
别名:ATF1; Activating transcription factor 1; Cyclic-AMP-dependent transcription factor ATF-1; TCR-ATF1; TREB36 protein应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| This protein binds the cAMP response element (CRE) (consensus: 5′-GTGACGT[AC][AG]-3′), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. Mackenzie KF, et al. (2013) J Immunol 190, 565-77 Dickinson RJ, et al. (2011) J Biol Chem 286, 38018-26 Wang J, Zhou JY, Wu GS (2011) J Biol Chem 286, 22384-92 |
| Specification | |
|---|---|
| Aliases | ATF1; Activating transcription factor 1; Cyclic-AMP-dependent transcription factor ATF-1; TCR-ATF1; TREB36 protein |
| Entrez GeneID | 466; |
| Swissprot | P18846 |
| WB Predicted band size | 29kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of serine 63(R-P-S(p)-Y-R) derived from Human ATF1 . |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HT29 cells treated with Insulin using Phospho-ATF1 (Ser63) antibody P40553.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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