别名:AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. |
Specification | |
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Aliases | AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1 |
Swissprot | Q13315 |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human ATM |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application | |
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IHC | 1/20-1/100 |
ELISA | 1/5000-1/10000 |
The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P06081(ATM Antibody) at dilution 1/30. (Original magnification: ×200) | |
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06081(ATM Antibody) at dilution 1/30. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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