Rabbit Polyclonal Antibody to ATP1α1/Na+K+ ATPase1 (Ab-23)

包装: 1G|100G|500G|1KG|100KG

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别名:A1A1; AT1A1; ATPase; Na+/K+ transporting; alpha 1 polypeptide
应用:WB,ICC
反应种属:Human
规格：50μl/100μl

Description
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.Shull G.E., Biochemistry 25:8125-8132(1986).Hara Y., J. Biochem. 102:43-58(1987).Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).

Description

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.Shull G.E., Biochemistry 25:8125-8132(1986).Hara Y., J. Biochem. 102:43-58(1987).Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).

Specification
Aliases	A1A1; AT1A1; ATPase; Na+/K+ transporting; alpha 1 polypeptide
Entrez GeneID	24211;
Swissprot	P06685
WB Predicted band size	113kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized non-phosphopeptide derived from human ATP1α1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
ICC	1/100-1/500

	Western blot analysis of extracts from HeLa cells, using ATP1α1/Na+K+ ATPase1 (Ab-23) antibody P41680.
	Western blot analysis of extracts from K562 cells (Lane 2), using ATP1α1/Na+K+ ATPase1 (Ab-23) antiobdy P41680. The lane on the left is treated with synthesized peptide.
	Immunofluorescence analysis of HeLa cells, using ATP1α1/Na+K+ ATPase1 (Ab-23) antibody P41680.