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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to AVP

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别名:Vasopressin-neurophysin 2-copeptin, AVP-NPII, Arg-vasopressin, Arginine-vasopressin, Neurophysin 2, Neurophysin-II, Copeptin, AVP, ARVP, VP
应用:WB,IHC,ICC
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a precursor protein consisting of
arginine vasopressin and two associated proteins, neurophysin 2 and
a glycopeptide, copeptin. Arginine vasopressin is a posterior
pituitary hormone which is synthesized in the supraoptic nucleus
and paraventricular nucleus of the hypothalamus. Along with its
carrier protein, neurophysin 2, it is packaged into neurosecretory
vesicles and transported axonally to the nerve endings in the
neurohypophysis where it is either stored or secreted into the
bloodstream. The precursor is thought to be activated while it is
being transported along the axon to the posterior pituitary.
Arginine vasopressin acts as a growth factor by enhancing pH
regulation through acid-base transport systems. It has a direct
antidiuretic action on the kidney, and also causes vasoconstriction
of the peripheral vessels. This hormone can contract smooth muscle
during parturition and lactation. It is also involved in cognition,
tolerance, adaptation and complex sexual and maternal behaviour, as
well as in the regulation of water excretion and cardiovascular
functions.
Specification
Aliases Vasopressin-neurophysin 2-copeptin, AVP-NPII, Arg-vasopressin, Arginine-vasopressin, Neurophysin 2, Neurophysin-II, Copeptin, AVP, ARVP, VP
Entrez GeneID 551
Swissprot P01185
WB Predicted band size 17.3kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This AVP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-129 amino acids of human AVP.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000
IHC 1/100-1/500
ICC 1/10-1/50

Anti-AVP Antibody (Center) at 1:1000 dilution + ZR-75-1 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 17 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

Confocal immunofluorescent analysis of AVP Antibody (Center)(Cat#P33513) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
AVP Antibody (Center) (Cat. #P33513) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AVP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。