Rabbit Polyclonal Antibody to AVPR1B

包装: 1G|100G|500G|1KG|100KG

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别名:Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3
应用:WB
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.

Description

The protein encoded by this gene acts as receptor for
arginine vasopressin. This receptor belongs to the subfamily of
G-protein coupled receptors which includes AVPR1A, V2R and OXT
receptors. Its activity is mediated by G proteins which stimulate a
phosphatidylinositol-calcium second messenger system. The receptor
is primarily located in the anterior pituitary, where it stimulates
ACTH release. It is expressed at high levels in ACTH-secreting
pituitary adenomas as well as in bronchial carcinoids responsible
for the ectopic ACTH syndrome. A spliced antisense transcript of
this gene has been reported but its function is not known.

Specification
Aliases	Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3
Entrez GeneID	553
Swissprot	P47901
WB Predicted band size	47.0kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.