别名:CT2.2应用:IHC
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2(B melanoma antigen 2), also known as Cancer/testis antigen 2.2, is 109 amino acid secreted proteins that is expressed in 22% of melanomas, lung and bladder carcinomas, and is also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. |
| Specification | |
|---|---|
| Aliases | CT2.2 |
| Swissprot | Q86Y30 |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human BAGE2 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| IHC | 1/25-1/100 |
| ELISA | 1/5000-1/10000 |
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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P12939(BAGE2 Antibody) at dilution 1/25. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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